Recombinant IL-11 Protein Summary
A partial protein corresponding to IL11.
E. coli expressed amino acids Pro22 - Leu199 (Accession # P20809.1)
|Details of Functionality
The ED50, as determined by the dose-dependent stimulation of mouse 7TD1 cell proliferation, is 1.9 ng/ml.
| Protein/Peptide Type
Partial Recombinant Protein
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
This protein was made to the human sequence.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid, phosphate buffered saline, pH 7.2, with 1.0% BSA. 0.22 um filtered.
0.09% Sodium Azide
Purity: Greater than 90%, as determined by reducing SDS-PAGE
Alternate Names for Recombinant IL-11 Protein
- Adipogenesis inhibitory factor
- interleukin 11
Human Interleukin-11 (IL-11) belongs to the IL-6 family of cytokines and is produced by bone marrow stromal cells, fibroblasts, epithelial cells, osteoclasts and other stromal cells. IL-11 is a pleiotropic cytokine that has been shown to have broad effects on many cell types. Among its effects are stimulation of megakaryocyte maturation, regulation of osteoblast growth and differentiation, enhanced platelet production (especially after trauma or homeostatic disruption), proliferation of lymphocytes and a protective role for gut epithelial cells. Mouse and human IL-11 share about 88% amino acid sequence identity.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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