IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free

Western Blot: IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free [NBP2-11654] - Lysate of human placenta tissue with mouse anti-human IL-10 R beta antibody.

• Reactivity: Hu
• Applications: WB, B/N
• Clone: MM0360-8R24
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free Summary

• Immunogen: Human recombinant IL-10 R beta (extracellular domain)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL10RB
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free

• CDw210b antigen
• CDw210b
• CRF2-4IL-10R subunit 2
• CRFB4
• CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B
• D21S58
• D21S66
• IBD25
• IL-10 R beta
• IL-10 receptor subunit beta
• IL10R beta
• IL-10R2
• IL-10R2IL-10R subunit beta
• IL10RB
• IL-10Rb
• interleukin 10 receptor, beta
• Interleukin-10 receptor subunit 2
• interleukin-10 receptor subunit beta
• member 4

Background

IL10RB, also known as Interleukin-10 receptor subunit beta, is a 325 amino acid protein that is 37 kDa; belongs to the type II cytokine receptor family; cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29; and its co-expression with IL10RA proteins is needed for IL10-induced signal transduction. This protein is currently being studied for research on several diseases and disorders including inflammatory bowel disease 25, early onset, autosomal recessive, hepatitis b virus, inflammatory bowel disease, hepatitis b, interferon, respiratory syncytial virus bronchiolitis, graft versus host disease, ulcerative colitis crohn's disease, anaplastic large cell lymphoma, secondary hyperparathyroidism, mumps, systemic lupus erythematosus, measles, bronchiolitis, rubella, cblc, lupus erythematosus, rheumatoid arthritis, colitis, and tumors. Interactions with IL10RB have been shown to involve IL22, UCN3, IL10RA, IL28A, and IL10 in cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, toxoplasmosis, tuberculosis, antioxidant action of vitamin-C, immune response IL-22 signaling pathway, and molecular mechanisms of cancer pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL10RB
• Uniprot:
  • Q08334()