IL-10 R alpha Antibody (RM0101-9E12)

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Immunohistochemistry-Paraffin: IL-10 R alpha Antibody (RM0101-9E12) [NBP1-22459] - The Kidney tissue samples from the Folic Acid induced kidney injury model were fixed using 4% PFA at 4C for overnight and embeded in ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC-P
Clone
RM0101-9E12
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
Unconjugated
Concentration
LYOPH

IL-10 R alpha Antibody (RM0101-9E12) Summary

Immunogen
Mouse recombinant protein of the Extracellular domain of IL-10R alpha
Specificity
This was produced from a hybridoma (mouse myeloma fused with spleen cells from a hamster immunized with mouse recombinant protein of extracellular domain of IL-10R alpha.
Isotype
IgG2
Clonality
Monoclonal
Host
Armenian Hamster
Gene
IL10RA
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry-Paraffin
Application Notes
This antibody detects mouse IL-10R alpha in Western blotting.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for IL-10 R alpha Antibody (RM0101-9E12)

  • CD210 antigen
  • CDw210a
  • HIL-10R
  • IBD28
  • IL-10 R alpha
  • IL-10 receptor subunit alpha
  • IL10R alpha
  • IL-10R subunit 1
  • IL-10R1
  • IL10RA
  • IL-10Ra
  • IL10RIL-10R subunit alpha
  • interleukin 10 receptor, alpha
  • interleukin-10 receptor alpha chain
  • Interleukin-10 receptor subunit 1
  • interleukin-10 receptor subunit alpha

Background

Interleukin 10 binds specifically and with high affinity to cell-surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IL10RA
Entrez