IL-1 RII Antibody

Images

 
There are currently no images for IL-1 RII Antibody (NBP1-52171).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated

Order Details

IL-1 RII Antibody Summary

Immunogen
Peptide with sequence C-QYNITRSIELRIKK corresponding to internal region according to NP_004624.1, NP_001248348.1.
Epitope
C-QYNITRSIELRIKK
Specificity
This antibody is expected to cross-react with both reported isoforms (NP_004624.1; NP_001248348.1). Reported variants represent identical protein: NP_775465.1, NP_004624.1
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
IL1R2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:2000
Application Notes
WB: Preliminary experiments gave an approx. 38 kDa band in human spleen lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 45.4 kDa band according to the precursor NP_004624.1 and 43.8 kDa band for the mature protein. The 38 kDa band was successfully blocked by incubation with the immunizing peptide.
Publications
Read Publication using NBP1-52171.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for IL-1 RII Antibody

  • beta
  • CD121b antigen
  • CD121b
  • IL-1 R beta
  • IL-1 RII
  • IL1R2
  • IL1RBCD121 antigen-like family member B
  • IL-1R-beta
  • IL1RII
  • IL-1RII
  • IL-1RT2
  • IL-1RT-2
  • interleukin 1 receptor, type II
  • Interleukin-1 receptor beta
  • MGC47725

Background

The antibody reacts specificly with Human IL-1RII. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. The IL-1RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signaling molecule which functions by capturing IL-1 and preventing it from interacting with the signalling IL-1RI. The decoy IL-1RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by coreceptor competition. Further a soluble form of IL-1RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF771
Species: Mu
Applications: WB, IHC, Neut
AF676
Species: Hu
Applications: WB, Flow, CyTOF-ready
AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
MAB208
Species: Hu
Applications: WB, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
NB100-56566
Species: Hu, Mu, Rt
Applications: WB, ChIP, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, CyTOF-ready, Flow-CS, Flow-IC
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
AF2940
Species: Hu
Applications: WB, Flow, CyTOF-ready
NBP1-82991
Species: Hu, Mu
Applications: WB, IHC, IHC-P
NBP1-52171
Species: Hu
Applications: PEP-ELISA

Publications for IL-1 RII Antibody (NBP1-52171)(1)

Reviews for IL-1 RII Antibody (NBP1-52171) (0)

There are no reviews for IL-1 RII Antibody (NBP1-52171). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for IL-1 RII Antibody (NBP1-52171) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional IL-1 RII Products

Bioinformatics Tool for IL-1 RII Antibody (NBP1-52171)

Discover related pathways, diseases and genes to IL-1 RII Antibody (NBP1-52171). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for IL-1 RII Antibody (NBP1-52171)

Discover more about diseases related to IL-1 RII Antibody (NBP1-52171).
 

Pathways for IL-1 RII Antibody (NBP1-52171)

View related products by pathway.

PTMs for IL-1 RII Antibody (NBP1-52171)

Learn more about PTMs related to IL-1 RII Antibody (NBP1-52171).
 

Research Areas for IL-1 RII Antibody (NBP1-52171)

Find related products by research area.

Blogs on IL-1 RII

There are no specific blogs for IL-1 RII, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our IL-1 RII Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol IL1R2
Entrez
Uniprot