IL-1 beta/IL-1F2 Partial Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary
Applications ELISA, IA
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

IL-1 beta/IL-1F2 Partial Recombinant Protein Summary

A partial protein corresponding to IL1B.
E. coli expressed amino acids Ala 117-Ser 269 of human IL-1b (accession # NM_000576).
Details of Functionality
Measured by mouse D10S cell proliferation assay. The ED50 is 100 pg/ml, corresponding to a specific activity of approximately 1x10^7Units/mg.
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid; phosphate buffered saline, pH 7.2, 150 mM NaCl, with no carriers. 0.22 um filtered.
No Preservative


  • Immunoassay
Application Notes
This reagent has been tested by sandwich ELISA using the anti-human IL-1beta ELISA pair (CRM56/CRM57).

Reactivity Notes

This protein was made to the human sequence.


Purity: Greater than 98%, as determined by SDS-PAGE

Alternate Names for IL-1 beta/IL-1F2 Partial Recombinant Protein

  • catabolin
  • IL1 beta
  • IL-1 beta
  • IL-1
  • IL1B
  • IL-1B
  • IL1-BETA
  • IL-1F2
  • IL1F2IL-1 beta
  • interleukin 1, beta
  • interleukin-1 beta
  • preinterleukin 1 beta
  • pro-interleukin-1-beta


Human IL-1beta, also called lymphocyte activating factor (LAF), endogenous pyrogen (EP), leucocyte endogenous mediator (LEM), mononuclear cell factor (MCF), is produced by a wide variety of cells, including macrophages, dendritic cells, T cells and B cells. IL-1beta is mostly released and has only 20% amino acid homology with IL-1alpha. The immune regulatory role of IL-1beta is exerted on a wide range of cells including lymphocytes, epithelial cells and fibroblasts. In vivo, it induces hypotension, fever, and acute phase response.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Blogs on IL-1 beta/IL-1F2.

IL-1 beta (interleukin 1 beta, lymphocyte activating factor (LAF))
IL-1 was originally identified and cloned as a lymphocyte mitogen and much later, was found to be comprised of two closely related but distinct proteins, interleukin 1 alpha (IL-1 alpha) and interleukin 1 beta (IL-1 beta). Both these proteins bind...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol IL1B

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