IL-1 beta/IL-1F2 Antibody (2A8)

Images

 
Western Blot: IL-1 beta/IL-1F2 Antibody (2A8) [H00003553-M01] - IL1B monoclonal antibody (M01), clone 2A8. Analysis of IL1B expression in human liver.
Immunocytochemistry/ Immunofluorescence: IL-1 beta/IL-1F2 Antibody (2A8) [H00003553-M01] - Analysis of monoclonal antibody to IL1B on HeLa cell. Antibody concentration 10 ug/ml.
Immunoprecipitation: IL-1 beta/IL-1F2 Antibody (2A8) [H00003553-M01] - Analysis of IL1B transfected lysate using anti-IL1B monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with IL1B MaxPab rabbit ...read more
Sandwich ELISA: IL-1 beta/IL-1F2 Antibody (2A8) [H00003553-M01] - Detection limit for recombinant GST tagged IL1B is approximately 10ng/ml as a capture antibody.

Product Details

Summary
Product Discontinued
View other related IL-1 beta/IL-1F2 Primary Antibodies

Order Details


    • Catalog Number
      H00003553-M01
    • Availability
      Product Discontinued

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IL-1 beta/IL-1F2 Antibody (2A8) Summary

Immunogen
IL1B (AAH08678 170 a.a. - 269 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS
Specificity
interleukin 1, beta
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IL1B
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • Immunoprecipitation
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
Publications
Read Publication using H00003553-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IL-1 beta/IL-1F2 Antibody (2A8)

  • catabolin
  • IL1 beta
  • IL-1 beta
  • IL-1
  • IL1B
  • IL-1b
  • IL1-BETA
  • IL-1F2
  • IL1F2IL-1 beta
  • interleukin 1, beta
  • interleukin-1 beta
  • preinterleukin 1 beta
  • pro-interleukin-1-beta

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IL-1 beta/IL-1F2 Antibody (H00003553-M01)(1)


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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Additional IL-1 beta/IL-1F2 Products

Bioinformatics Tool for IL-1 beta/IL-1F2 Antibody (H00003553-M01)

Discover related pathways, diseases and genes to IL-1 beta/IL-1F2 Antibody (H00003553-M01). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for IL-1 beta/IL-1F2 Antibody (H00003553-M01)

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Pathways for IL-1 beta/IL-1F2 Antibody (H00003553-M01)

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PTMs for IL-1 beta/IL-1F2 Antibody (H00003553-M01)

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Research Areas for IL-1 beta/IL-1F2 Antibody (H00003553-M01)

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Blogs on IL-1 beta/IL-1F2.

IL-1 beta (interleukin 1 beta, lymphocyte activating factor (LAF))
IL-1 was originally identified and cloned as a lymphocyte mitogen and much later, was found to be comprised of two closely related but distinct proteins, interleukin 1 alpha (IL-1 alpha) and interleukin 1 beta (IL-1 beta). Both these proteins bind...  Read full blog post.

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Bioinformatics

Gene Symbol IL1B
Entrez
OMIM
Uniprot