Recombinant Human IL-1 alpha/IL-1F1 Protein Summary
A partial protein corresponding to IL1A.
|Details of Functionality
Measured by mouse D10S cell proliferation assay. The ED50 of 20 pg/ml, corresponding to a specific activity of approximately 5x10^7Units/mg.
| Protein/Peptide Type
Partial Recombinant Protein
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
The recombinant human IL-1α has been tested as the standard in a human IL-1α sandwich ELISA using the human IL-1α ELISA pair (CRM8/CRM6).
This protein was made to the human sequence.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid; 20 mM tris, 0.2 M NaCl, 1 mM DTT, pH 8.0 with no carriers or stabilizers. 0.22 um filtered.
0.09% Sodium Azide
Purity: Greater than 98%, as determined by SDS-PAGE
Alternate Names for Recombinant Human IL-1 alpha/IL-1F1 Protein
- IL1 alpha
- IL-1 alpha
- interleukin 1, alpha
- interleukin-1 alpha
- preinterleukin 1 alpha
Human IL-1alpha, also called lymphocyte activating factor (LAF), endogenous pyrogen (EP), leucocyte endogenous mediator (LEM), and mononuclear cell factor (MCF), is produced by a wide variety of cells, including macrophages, dendritic cells, T cells and B cells. IL-1alpha is mostly cell associated and has only 20% amino acid homology with IL-1beta. The immune regulatory role of IL-1alpha is exerted on a wide range of cells including lymphocytes, epithelial cells and fibroblasts. In vivo, it induces hypotension, fever, and acute phase response.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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