IKEPP Antibody

Images

 
Western Blot: IKEPP Antibody [H00079849-D01P] - Analysis of PDZD3 expression in transfected 293T cell line by PDZD3 polyclonal antibody.Lane 1: PDZD3 transfected lysate(52.50 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

IKEPP Antibody Summary

Immunogen
PDZD3 (NP_079067.2, 1 a.a. ~ 491 a.a) full-length human protein.MEKAADLQDTASLTLKFKFNPKLGIDNPVLSLAEDHDPYDPWSLERPRFCLLSKEEGKSFGFHLQQELGRAGHVVCRVDPGTSAQRQGLQEGDRILAVNNDVVEHEDYAVVVRRIRASSPRVLLTVLARHAHDVARAQLGEDAHLCPTLGPGVRPRLCHIVKDEGGFGFSVTHGNQGPFWLVLSTGGAAERAGVPPGARLLEVNGLWQSGQQVTLLVAGPEVEEQCRQLGLPLAAPLAEGWALPTKPRCLHLEKG
Specificity
PDZD3 - PDZ domain containing 3,
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDZD3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IKEPP Antibody

  • FLJ22756
  • IKEPPPDZK2
  • intestinal and kidney enriched PDZ protein
  • Intestinal and kidney-enriched PDZ protein
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF4
  • Na/Pi cotransporter C-terminal-associated protein 2
  • naPi-Cap2
  • Natrium-phosphate cotransporter IIa C-terminal-associated protein 2
  • NHERF4
  • NHERF-4
  • PDZ domain containing 2
  • PDZ domain containing 3
  • PDZ domain-containing protein 2
  • PDZ domain-containing protein 3
  • Sodium-hydrogen exchanger regulatory factor 4

Background

Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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H00079849-D01P
Species: Hu
Applications: WB, ELISA

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PDZD3
Entrez
Uniprot