IkB-alpha [p Tyr42] Antibody


Western Blot: IkB-alpha [p Tyr42] Antibody [NBP1-51433] - Analysis of p-IkB-alpha (Y42) pAb at 1:500 dilution Lane1:Hela cell lysate treated with forskolin (10nM, 72h) Lane2:Raw264.7 cell lysate treated with forskolin ...read more
Immunohistochemistry-Paraffin: IkB-alpha [p Tyr42] Antibody [NBP1-51433] - Analyzes of p-IkB-alpha (Y42) pAb in paraffin-embedded human breast carcinoma tissue.

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IkB-alpha [p Tyr42] Antibody Summary

Synthetic phosphopeptide derived from human IkB-alpha around the phosphorylation site of Tyrosine 42.
p Tyr42
p-IkappaB-alpha (Y42) pAb detects endogenous levels of IkappaB-alphaprotein only when phosphorylated at Y42.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Immunohistochemistry (IHC) analyzes of p-IkB-alpha (Y42) pAb in paraffin-embedded human breast carcinoma tissue.
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for IkB-alpha [p Tyr42] Antibody

  • alpha
  • I-kappa-B-alpha
  • IkappaBalphaNF-kappa-B inhibitor alpha
  • IKBAikB-alpha
  • IkBalpha
  • IkB-alpha
  • MAD3
  • MAD-3
  • Major histocompatibility complex enhancer-binding protein MAD3
  • nuclear factor of kappa light chain gene enhancer in B-cells
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor


On the basis of both functional and structural considerations, members of the IkB family of proteins can be divided into four groups. The first of these groups, IkB-alpah (a 35-37 kDa protein), includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kB sites, suggesting that the IkB-alpha family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkB family is represented by a 45 kDa protein designated IkB-beta. The third group of IkB proteins is represented by Ik B-gamma, a 70 kDa protein identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and expressed predominantly in lymphoid cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol NFKBIA