IGF-I R Antibody


Western Blot: IGF-I R Antibody [NBP1-77680] - Analysis of IGFR1 in: 1. HeLa, 2. NIH/3T3, 3. SK-BR-3 and 4. COS7.
Immunocytochemistry/ Immunofluorescence: IGF-I R Antibody [NBP1-77680] - IGF1 receptor (EC) antibody was tested in A431 cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).
Western Blot: IGF-I R Antibody [NBP1-77680] - Analysis of IGF-I R in human pancreatic cancer cell lines (MiaPaCa-2, AsPC-1, and BxPC-3) using anti-IGF-I R antibody. Image from verified customer review.

Product Details

Reactivity Hu, Mu, Rt, Eq, PmSpecies Glossary
Applications WB, ICC/IF
1.09 mg/ml

IGF-I R Antibody Summary

A synthetic peptide made to an internal portion of the human IGF1 Receptor protein (between residues 700-800) [UniProt P08069]
Predicted Species
Bovine (100%)
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, 30% glycerol
0.05% Sodium Azide
1.09 mg/ml
Immunogen affinity purified


Application Notes
This IGFR1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot where a band is seen ~100 kDa.
Reviewed Applications
Read 1 Review rated 4
NBP1-77680 in the following application:

Read Publication using
NBP1-77680 in the following applications:

  • WB
    1 publication

Reactivity Notes

Human, rat, mouse and primate. Reactivity with Equine reported via customer feedback. Predicted to react with Bovine (100%).

Alternate Names for IGF-I R Antibody

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC
  • IGF1R
  • IGF-I receptor
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2


Insulin-like growth factor receptor 1 (IGFR1) is a tyrosine kinase receptor that is important in embryonic development. IGFR1 has effects in breast, prostate, gastric and lung cancers, as it can be a player in drug resistance. It also affects the flow of nutrients from mother to placenta to fetus during development. IGFR1 seems to greatly influence the rate of growth of fetuses and newborn babies; when it is not appropriately expressed or regulated, fetal growth restriction occurs. The major activity of IGFR1 is to mediate the signaling of growth signals to effect downstream growth patterns.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IGF-I R Antibody (NBP1-77680)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

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Reviews for IGF-I R Antibody (NBP1-77680) (1) 41

Average Rating: 4
(Based on 1 reviews)
We have 1 review tested in 1 species: Other.
We have 1 review tested in 1 application: WB.

Reviews using NBP1-77680:
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Images Ratings Applications Species Date Details
Western Blot IGF-I R NBP1-77680
reviewed by:
WB Other 02/04/2016


ApplicationWestern Blot
Sample TestedHuman pancreatic cancer cell lines MiaPaCa-2, AsPC-1, and BxPC-3


Blocking DetailsLiCor Odyssey Blocking Buffer (PBS), 4 hour, room temperature

Primary Anitbody

Dilution RatioDilution 1:1000, 8 hour, room temperature, LiCor Odyssey Blocking Buffer (PBS) w/0.2% Tween 20

Secondary Antibody

Secondary DescriptionDonkey anti-Rabbit 800 CW
Secondary Manufacturer Cat#925-32213
Secondary Concentration1 mg/ mL, Dilution 1:15,000


Detection NotesFluorescence detection, LiCor Odyssey, Scan time 4-6 min, Positive MiaPaCa-2 and Negative BxPC-3


CommentsWe found this antibody to work well for this particular experiment. In our lab, we only want to make sure that our novel imaging agents are targeted to tumors that express the receptor of interest. The delivery time was fast and the company was very nice. Yes, there are some non-specific bands in the blot, yet this is a common occurrence with polyclonal antibodies.

Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for IGF-I R Antibody (NBP1-77680). (Showing 1 - 1 of 1 FAQ).

  1. Our customer would like to perform IHC with samples from Rat. She has questions regarding antibodies of choice: 1. Is it possible to use NB400-142 for IHC? 2. I am having difficulty of choosing between NBP1-77679 and NBP1-77680. Would you please help suggest? 3. Although it is described as IHC (-) on the product page of NBP1-07034, This antibody did not work in IHC with mouse tissue is also described. How about Rat samples? Is it possible that the antibody can work in IHC with rat tissues?
    • To answer your questions about NB400-142, this antibody has not been validated for IHC and we cannot guarantee that it will work. Both NBP1-77679 and NBP1-77680 have been validated for use in rat and IHC. The difference between these 2 antibodies is the immunogen as they were raised against different regions of the protein. Please point out the immunogen to your customer and have them decide what would be best for their research. NBP1-07034 does not work in IHC, it is only guaranteed for Western blot in human, mouse and rat. When an application is followed by a (-) I would not recommend using this application in any species.

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP1-77680AF405
Alexa Fluor (R) 488 Labeled NBP1-77680AF488
Alexa Fluor (R) 647 Labeled NBP1-77680AF647
Alexa Fluor (R) 700 Labeled NBP1-77680AF700
Biotin Labeled NBP1-77680B
DyLight 405 Labeled NBP1-77680V
DyLight 488 Labeled NBP1-77680G
DyLight 550 Labeled NBP1-77680R
DyLight 650 Labeled NBP1-77680C
FITC Labeled NBP1-77680F
HRP Labeled NBP1-77680H

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Contact Information

Product PDFs


Gene Symbol IGF1R

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