IGF-I R Antibody (1H7)

Images

 
Flow Cytometry: IGF-I R Antibody (1H7) [NB100-66537] - Staining of human peripheral blood granulocytes with mouse anti human CD221 (NB100-66537).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, IHC-P
Clone
1H7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

IGF-I R Antibody (1H7) Summary

Immunogen
Purified human placental IGF-I receptor
Specificity
NB100-66537 recognizes human CD221
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGF1R
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Flow Cytometry 1:10
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:40
Application Notes
For Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. This product requires protein digestion pretreatment of paraffin sections e.g. trypsin or pronase.
Positive Control
IGF-I R Lysate (NBL1-11867)

Reactivity Notes

Reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for IGF-I R Antibody (1H7)

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC 2.7.10.1
  • IGF1R
  • IGF-I R
  • IGF-I receptor
  • IGFIR
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2

Background

There are two kinds of IGF receptors based on their relative affinities for IGF1 versus IGF2. The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-12793
Species: Hu, Mu
Applications: WB, IP
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
NB100-56749
Species: Hu, Mu
Applications: WB, IHC, IHC-P
AF3978
Species: Hu, Mu, Rt
Applications: WB, IHC
AF231
Species: Hu
Applications: WB, Flow, IHC, IP, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ELISA(Sta)
NBP2-22203
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
AF1067
Species: Hu, Mu, Rt
Applications: WB, IHC, Neut
AF1067
Species: Hu, Mu, Rt
Applications: WB, IHC, Neut
AF1360
Species: Mu
Applications: WB, IHC
NB300-514
Species: Hu, Mu, Rt, Bv, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, IP, CyTOF-ready
AF875
Species: Hu
Applications: WB, IHC
NB100-66537
Species: Hu
Applications: WB, Flow, IHC, IHC-P

Publications for IGF-I R Antibody (NB100-66537) (0)

There are no publications for IGF-I R Antibody (NB100-66537).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for IGF-I R Antibody (NB100-66537) (0)

There are no reviews for IGF-I R Antibody (NB100-66537). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for IGF-I R Antibody (NB100-66537) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NB100-66537AF405
Alexa Fluor 488 Labeled NB100-66537AF488
Alexa Fluor 647 Labeled NB100-66537AF647
Alexa Fluor 700 Labeled NB100-66537AF700
Allophycocyanin Labeled NB100-66537APC
DyLight 350 Labeled NB100-66537UV
DyLight 405 Labeled NB100-66537V
DyLight 488 Labeled NB100-66537G
DyLight 680 Labeled NB100-66537FR
DyLight 755 Labeled NB100-66537IR
PE Labeled NB100-66537PE
PerCP Labeled NB100-66537PCP

Additional IGF-I R Products

Bioinformatics Tool for IGF-I R Antibody (NB100-66537)

Discover related pathways, diseases and genes to IGF-I R Antibody (NB100-66537). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for IGF-I R Antibody (NB100-66537)

Discover more about diseases related to IGF-I R Antibody (NB100-66537).
 

Pathways for IGF-I R Antibody (NB100-66537)

View related products by pathway.

PTMs for IGF-I R Antibody (NB100-66537)

Learn more about PTMs related to IGF-I R Antibody (NB100-66537).
 

Research Areas for IGF-I R Antibody (NB100-66537)

Find related products by research area.

Blogs on IGF-I R

There are no specific blogs for IGF-I R, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our IGF-I R Antibody (1H7) and receive a gift card or discount.

Bioinformatics

Gene Symbol IGF1R
Entrez
Uniprot