IGF-I R Antibody (1H7)


Flow Cytometry: IGF1 Receptor Antibody (1H7) [NB100-66537] - Staining of human peripheral blood granulocytes with mouse anti human CD221 (NB100-66537).

Product Details

Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, IHC-P
1.0 mg/ml

IGF-I R Antibody (1H7) Summary

Purified human placental IGF-I receptor
NB100-66537 recognizes human CD221
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, pH 7.4
0.09% Sodium Azide
1.0 mg/ml
Protein G purified


  • Western Blot 1:100-1:2000
  • Flow Cytometry 1:10
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:40
Application Notes
For Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. This product requires protein digestion pretreatment of paraffin sections e.g. trypsin or pronase.

Reactivity Notes

Reacts with Human.

Alternate Names for IGF-I R Antibody (1H7)

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC
  • IGF1R
  • IGF-I receptor
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2


There are two kinds of IGF receptors based on their relative affinities for IGF1 versus IGF2. The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for IGF-I R Antibody (NB100-66537) (0)

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB100-66537AF405
Alexa Fluor (R) 488 Labeled NB100-66537AF488
Alexa Fluor (R) 647 Labeled NB100-66537AF647
Alexa Fluor (R) 700 Labeled NB100-66537AF700
Allophycocyanin Labeled NB100-66537APC
DyLight 350 Labeled NB100-66537UV
DyLight 405 Labeled NB100-66537V
DyLight 405LS Labeled NB100-66537V3
DyLight 488 Labeled NB100-66537G
DyLight 680 Labeled NB100-66537FR
DyLight 755 Labeled NB100-66537IR
PE Labeled NB100-66537PE
PerCP Labeled NB100-66537PCP

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Contact Information

Product PDFs


Gene Symbol IGF1R

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