IGF-I R Antibody (17-69)

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Product Details

Summary
Reactivity Hu, Po, RbSpecies Glossary
Applications IP, InhibAct
Clone
17-69
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

IGF-I R Antibody (17-69) Summary

Immunogen
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Epitope
aa 514-586 (exon 7/8)
Localization
Cell membrane
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGF1R
Purity
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 2 ug/ml
  • Inhibition Activity
Publications
Read Publication using NB500-705.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4) and BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein G purified

Alternate Names for IGF-I R Antibody (17-69)

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC 2.7.10.1
  • IGF1R
  • IGF-I R
  • IGF-I receptor
  • IGFIR
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2

Background

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of a- and a-subunits, which are disulfide-linked in a a-a-a-a configuration in the mature receptor. The a-subunit is completely extracellular, while the a-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IGF-I R Antibody (NB500-705)(1)


Showing Publication 1 - 1 of 1.
Publication using NB500-705 Applications Species
Dziadziuszko R, Merrick D T, Szostakiewicz B et al. High Insulin-like Growth Factor 1 Receptor (Igf1r) Expression Is Associated with Poor Survival in Surgically Treated Patients with Non-Small Cell Lung Cancer (Nsclc). 12th World Conference on Lung Cancer - International Association for the Study of Lung Cancer (IASLC) Seoul; Korea. 2-Sep-07.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IGF1R
Entrez
Uniprot