IGF-I Partial Recombinant Protein


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Product Details

Reactivity MuSpecies Glossary
Applications IA
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

IGF-I Partial Recombinant Protein Summary

A partial protein corresponding to IGF1.
E. coli-expressed amino acids Gly33 - Ala102 (Accession# NP001104746).
Details of Functionality
This reagent has been tested in bioassays using the FDC-P1 cell line. The ED50, measured by the dose-dependent induction of FDC-P1 cell proliferation is typically 2 ng/ml, corresponding to a specific activity of approximately 5 x10^5 Units/mg.
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid, phosphate buffered saline, pH 7.2, with 1.0% BSA. 0.22 um filtered.
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.

Reactivity Notes

This protein was made to the Mouse sequence.


Purity: Greater than 98%, as determined by SDS-PAGE

Alternate Names for IGF-I Partial Recombinant Protein

  • IBP1
  • IGF1
  • IGF-1
  • IGF1A
  • IGFI
  • IGF-I
  • IGF-IA
  • IGF-IB
  • insulin-like growth factor 1 (somatomedin C)
  • insulin-like growth factor 1
  • insulin-like growth factor I
  • insulin-like growth factor IA
  • insulin-like growth factor IB
  • Mechano growth factor
  • MGF
  • Somatomedin A
  • Somatomedin C
  • somatomedin-C


Insulin-like growth factor I (IGF-1), also known as somatomedin C, is a member of the insulin-like growth factor family. This protein is expressed in many cell types and is secreted into the blood. Metabolism of glucose, fatty acids, cartilage and bone, as well as growth hormone activity, are all regulated by IGF-1. This protein also plays important roles in Alzheimers disease and tumor pathogenesis. IGF-1 and IGF-2 share 70% sequence identity. Furthermore, mature mouse IGF1 shares 94% and 99% amino acid sequence identity with human and rat IGF1, respectively, and exhibits cross-species activity. Recombinant mouse IGF-1 produced in E.coli is a single, non-glycosylated, polypeptide containing 70 amino acids.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol IGF1

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