IgE Antibody (BE5) [FITC]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-44927
    • Availability
      Product Discontinued

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IgE Antibody (BE5) [FITC] Summary

Immunogen
Purified human IgE.
Specificity
The antibody BE5 reacts with human IgE; it recognizes an epitope different from the ones recognized by 4G7 and 4H10 antibodies to IgE.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGHE
Purity
Ion exchange chromatography
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Applications/Dilutions

Dilutions
  • ELISA 1:2000
  • Flow Cytometry 1:10-1:1000

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Concentration
0.1 mg/ml
Purity
Ion exchange chromatography

Notes

Store in the dark. Avoid prolonged exposure to light.

Alternate Names for IgE Antibody (BE5) [FITC]

  • IgE
  • immunoglobulin heavy constant epsilon

Background

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional IgE Products

Bioinformatics Tool for IgE Antibody (NBP1-44927)

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Diseases for IgE Antibody (NBP1-44927)

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Pathways for IgE Antibody (NBP1-44927)

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Research Areas for IgE Antibody (NBP1-44927)

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Blogs on IgE.

Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains...  Read full blog post.

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Bioinformatics

Gene Symbol IGHE