IFN-gamma R1/CD119 Antibody (A6C5)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC, IHC-Fr
Clone
A6C5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

IFN-gamma R1/CD119 Antibody (A6C5) Summary

Immunogen
rhuIFN gamma adsorbed with lysates of enriched Raji cell membranes
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IFNGR1
Purity
Ion exchange chromatography
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1-10 ug/ml
  • Immunohistochemistry 1-10 ug/ml
  • Immunohistochemistry-Frozen 1-10 ug/ml

Reactivity Notes

human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Tris-NaCl (pH 8.0)
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Ion exchange chromatography

Notes

This product is manufactured by Dendritics and distributed by Novus Biologicals in North America and other select countries. To order in the following countries: Germany, Finland, United Kingdom, Norway, Denmark, Switzerland, Austria and South Korea, please contact Dendritics for additional ordering information.

Alternate Names for IFN-gamma R1/CD119 Antibody (A6C5)

  • AVP, type 2
  • CD119 antigen
  • CD119
  • FLJ45734
  • IFN-gamma R1
  • IFN-gamma receptor 1
  • IFNgammaR1
  • IFN-gamma-R1
  • IFNGR
  • IFNGR1
  • IFN-gR1
  • immune interferon receptor 1
  • interferon gamma receptor 1
  • interferon-gamma receptor alpha chain
  • type 2

Background

Activities of IFN gamma are initiated by binding to species-specific cell surface receptors. IFN gamma-R binds IFN with high affinity. CD119 belongs to the cytokine type-II receptor family and is expressed on monocytes, macrophages, T and B cells, NK cells, neutrophils, fibroblasts, epithelial cells and a wide range of tumour macrophages, T and B cells, NK cells, neutrophils, fibroblasts, epithelial cells and a wide range of tumour cells. The CD119 receptor plays a role in host defense and immunological processes, in macrophage and NK cells activation, in B and T cell differentiation, and up-regulates the expression of MHC class I and II antigens in several cellular types. (Pfizenmaier K. et al, J. Immunol, 1988, 141-856; Ucer U. et al, 1986, Canc.Res.,46: 5339-5343)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol IFNGR1
Entrez