IFN-beta Recombinant Protein Summary
A recombinant protein corresponding to amino acids 22 - 182 of IFNB1.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN
>95% pure by SDS-PAGE
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
In 20mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl, 30% glycerol
>95% pure by SDS-PAGE
The purity of this protein is > 95% by SDS-PAGE. Molecular weight is 22.0 kDa (182 aa), confirmed by MALDI-TOF.
Alternate Names for IFN-beta Recombinant Protein
- Fibroblast interferon
- interferon beta
- interferon, beta 1, fibroblast
Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis. Recombinant Interferon beta 1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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