IFN-alpha 2 Partial Recombinant Protein Summary
A partial protein corresponding to IFNA2.
E. coli expressed amino acids Cys24-Glu190 of mature mouse Interferon alpha 2 (accession # NM_010503).
|Details of Functionality
The recombinant mouse IFN-a2 has been tested for inhibition of the cytopathic effect of EMC virus on L929 cells. The ED50 for this effect is typically 0.1 ng/ml, corresponding to a specific activity of 1 x 107 U/mg.
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid; 20 mM sodium phosphate, pH 7.2, 150 mM NaCl, with 0.5% BSA. 0.22 uM filtered.
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
The recombinant mouse IFN-alpha2 has been tested for inhibition of the cytopathic effect of EMC virus on L929 cells. The ED,50 for this effect is typically 0.1 ng/ml, corresponding to a specific activity of 1 x 10^7 U/mg.
This protein was made to the mouse sequence.
Purity: Greater than 98% as determined by SDS-PAGE
Alternate Names for IFN-alpha 2 Partial Recombinant Protein
- alpha-2a interferon
- IFNalpha 2
- interferon alpha 2b
- interferon alpha A
- interferon alpha-2
- Interferon alpha-A
- interferon, alpha 2
- LeIF A
IFN-alpha2 is a type I interferon, previously known as B-cell interferon, leukocyte interferon, lymphoblast interferon, and pH2-stable interferon. IFN-alpha2 is one of at least 23 different known variants of IFN-alpha. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. IFN-alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances (n-butyrate, 5-bromodeoxyuridine). IFN-alpha2 demonstrates antiviral, antiparasitic, antiproliferative activities.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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