ICAM-1/CD54 Antibody Summary
Synthetic peptide, corresponding to amino acids 471-520 of Human ICAM-1.
Immunogen affinity purified
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, pH 7.2.
0.05% Sodium Azide
Immunogen affinity purified
Western blot (WB) analysis of ICAM1 (Q506) pAb in extracts from HepG2 cells.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
This antibody is reactive against Human
Alternate Names for ICAM-1/CD54 Antibody
- CD54 antigen
- cell surface glycoprotein P3.58
- human rhinovirus receptor
- intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
- intercellular adhesion molecule 1
- Major group rhinovirus receptor
ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase in inflammation. Also, ICAM1 is detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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