HVEM/TNFRSF14 Antibody (122)


Flow Cytometry: HVEM/TNFRSF14 Antibody (122) [NB100-78025] - Human peripheral blood lymphocytes stained with purified 122, followed by biotinylated anti-mouse IgG and Sav-PE.

Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow
0.5 mg/ml

HVEM/TNFRSF14 Antibody (122) Summary

recombinant humanHVEM protein
HVEM (122)
IgG1 Kappa
Affinity purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
PBS [pH 7.2]
0.09% Sodium Azide
0.5 mg/ml
Affinity purified


Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Alternate Names for HVEM/TNFRSF14 Antibody (122)

  • ATAR
  • CD270 antigen
  • CD270
  • CD40-like protein
  • Herpes virus entry mediator A
  • Herpesvirus entry mediator A
  • HveA
  • TNFRSF14
  • tumor necrosis factor receptor superfamily member 14
  • tumor necrosis factor receptor superfamily, member 14 (herpesvirus entrymediator)
  • Tumor necrosis factor receptor-like 2
  • tumor necrosis factor receptor-like gene2


The 122 antibody recognizes human HVEM also known as herpesvirus entry mediator A, tumor necrosis factor receptor superfamily, member 14, TNFRSF14, and tumor necrosis factor receptor like 2. HVEM, a member of the TNFR superfamily, is a type I transmembrane protein containing 2 TNF receptor domains with a predicted molecular weight of approximately 30 kD. HVEM is widely expressed in blood vessels, brain, heart, kidney, liver, lung, prostate, spleen, thymus and other organs. Resting T cells and na iumlve and memory B cells express high levels of HVEM as well.In humans, HVEM is not expressed in germinal center B cells. Immature dendritic cells express high levels of HVEM that is downregulated upon maturation. HVEM plays an important role in herpes simplex virus pathogenesis by enhancing entry into cells. Signaling through HVEM activates JNK1, NF- kappaB and AP-1 to control gene expression in response to infection or cellular stress and activate the immune response. HVEM binds to LIGHT and has also been shown to associate with several other proteins including TRAF1, TRAF2, TRAF3, TRAF5, B and T lymphocyte associated protein (BTLA), and estrogen receptor alpha. The 122 antibody has been shown to be useful for flow cytometry, Western blot, and ELISA.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for HVEM/TNFRSF14 Antibody (NB100-78025) (0)

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB100-78025AF405
Alexa Fluor (R) 488 Labeled NB100-78025AF488
Alexa Fluor (R) 647 Labeled NB100-78025AF647
Alexa Fluor (R) 700 Labeled NB100-78025AF700
Allophycocyanin Labeled NB100-78025APC
DyLight 350 Labeled NB100-78025UV
DyLight 405 Labeled NB100-78025V
DyLight 405LS Labeled NB100-78025V3
DyLight 488 Labeled NB100-78025G
DyLight 680 Labeled NB100-78025FR
DyLight 755 Labeled NB100-78025IR
PE Labeled NB100-78025PE
PerCP Labeled NB100-78025PCP

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Contact Information

Product PDFs


Gene Symbol TNFRSF14

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