Huntingtin Antibody Summary
The immunogen for this product maps to a region between residue 2300 and 2350 of human Huntingtin using the numbering given in entry NP_002102.4 (GeneID 3064).
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Immunoprecipitation 2-5 ug/mg lysate
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
0.09% Sodium Azide
Immunogen affinity purified
Alternate Names for Huntingtin Antibody
- HD protein
- huntingtin (Huntington disease)
- IT15HDHuntington disease protein
Huntingtin (also known as Huntington's disease protein, Htt and HD protein) is the protein product of a disease gene linked to Huntington's disease, a neuro-degenerative disorder characterized by loss of striatal neurons. This may be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product (see partial protein sequence below). The huntingtin gene locus is large, spanning 180 kb and consisting of 67 exons. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein. One candidate is the huntingtin-associated protein-1, highly expressed in brain, which has increased affinity for huntingtin protein with expanded polyglutamine repeats. Normal huntingtin protein shows a cytoplasmic localization. This protein is widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, PEP-ELISA
Applications: WB, ELISA, ICC/IF
Species: Hu, Mu, Rt, Ca, Eq
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
Species: Hu, Po, Rb
Applications: WB, B/N, ELISA, ICC/IF, IHC, IHC-P, RIA
Species: Hu, Mu, Rt, Po, ChHa, Ma
Applications: WB, Simple Western, EM, Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, CyTOF-ready, KO
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IF
Publications for Huntingtin Antibody (NBP1-47279) (0)
There are no publications for Huntingtin Antibody (NBP1-47279).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for Huntingtin Antibody (NBP1-47279) (0)
There are no reviews for Huntingtin Antibody (NBP1-47279).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
- 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for Huntingtin Antibody (NBP1-47279) (0)
Additional Huntingtin Products
Bioinformatics Tool for Huntingtin Antibody (NBP1-47279)
Discover related pathways, diseases and genes to Huntingtin Antibody (NBP1-47279). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on Huntingtin