Huntingtin Antibody (1D1)


Immunocytochemistry/ Immunofluorescence: Huntingtin Antibody (1D1) [H00003064-M18] - Analysis of monoclonal antibody to HTT on HeLa cell. Antibody concentration 10 ug/ml

Product Details

Reactivity HuSpecies Glossary
Applications ELISA, ICC/IF
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Order Details

Huntingtin Antibody (1D1) Summary

HD (NP_002102, 1524 a.a. ~ 1627 a.a) full length recombinant protein with GST tag.
HD (1D1)
IgG2b Kappa
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
IgG purified


Application Notes
This antibody is useful for ELISA.

Reactivity Notes

Human. Other species not tested.


This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Huntingtin Antibody (1D1)

  • HD protein
  • huntingtin (Huntington disease)
  • huntingtin
  • IT15HDHuntington disease protein


Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range in the number of trinucleotide repeats has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal development. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed. The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein. One candidate is the huntingtin-associated protein-1, highly expressed in brain, which has increased affinity for huntingtin protein with expanded polyglutamine repeats. This gene contains an upstream open reading frame in the 5' UTR that inhibits expression of the huntingtin gene product through translational repression.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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Bioinformatics Tool for Huntingtin Antibody (H00003064-M18)

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Contact Information

Product PDFs


Gene Symbol HTT

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