Humanin Antibody - BSA Free

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Western Blot: Humanin Antibody [NB100-56876] - Analysis of human humanin in (A) recombinant fusion protein containing amino acids 12-24 and (B) fusion partner without these amino acids, using this antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

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Catalog# & Formulation Size Price

Humanin Antibody - BSA Free Summary

Immunogen
Amino acids 12-24 of human humanin protein were used as the immunogen.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MTRNR2L1
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:1000
  • Western Blot 1:2000
Publications
Read Publication using NB100-56876.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Whole antisera with 50% Glycerol
Preservative
0.025% Sodium Azide
Purity
Unpurified

Alternate Names for Humanin Antibody - BSA Free

  • HN
  • HUNIN

Background

Humanin is a novel 24 A.A polypeptide identified in Alzheimer's disease-affected brain. It is 99% homologous to mitochondrial 16s ribosomal RNA and functions as a novel neuroprotective and cytoprotective factor. It specifically inhibits neuronal cell death induced by beta-amyloids and Alzheimer's disease causing FAD genes by competitively inhibiting access of FPRL1 receptor to beta-amyloids. It acts as an anti-apoptotic factor by binding to Bcl-2/Bax family of pro-apoptotic factors including Bax, Bak, Bid and BimEL and inhibits their pro-apoptotic activity. It activates JAK/STAT signaling pathway and is regulated by TRIM11. It interacts with IGFBP-3 and specifically blocks IGFBP-3 induced cell death in glioblastoma cells. Humanin is also expressed in colon and testis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Humanin Antibody (NB100-56876)(1)

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Bioinformatics

Gene Symbol MTRNR2L1
Uniprot