Human Trypsin Pan Specific DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Trypsin Pan Specific DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Trypsin Pan Specific DuoSet ELISA, 15 Plate

• TRY2
• TRY8
• TRYP2
• Trypsin

Background

PRSS (Protease; serine) genes produce three isoforms of pancreatic trypsinogen. Based on their electrophoretic mobilities, they are named cationic trypsinogen (trypsin 1/PRSS1), anionic trypsinogen (trypsin 2/PRSS2) and meso- (or "in the middle") trypsinogen (trypsin 3/PRSS3). PRSS1 is the predominant form (67%). Following secretion from the pancreas, active trypsin is generated in the duodenum through the interaction of brush-border duodenal enterokinase with trypsinogen.

Publications for Trypsin Pan Specific/PRSS1/2/3 (DY3586)(2)

Publications using DY3586

• KK Kim, R Turner, N Khazan, A Kodza, A Jones, RK Singh, RG Moore Role of trypsin and protease-activated receptor-2 in ovarian cancer PLoS ONE, 2020-05-04;15(5):e0232253. 2020-05-04 [PMID: 32365084] (Human)
• Z Tan, L Gao, Y Wang, H Yin, Y Xi, X Wu, Y Shao, W Qiu, P Du, W Shen, L Fu, R Jia, C Zhao, Y Zhang, Z Zhao, Z Sun, H Chen, X Hu, J Xu, Y Wang PRSS contributes to cetuximab resistance in colorectal cancer Sci Adv, 2020-01-01;6(1):eaax5576. 2020-01-01 [PMID: 31911942] (Human)