HtrA3 Antibody

Images

 
Western Blot: HtrA3 Antibody [NBP1-39951] - Western blot analysis of HtrA3 in rat heart lysate using antibody at 2 ug/ml.
Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-39951] - Staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ...read more

Product Details

Summary
Product Discontinued
View other related HtrA3 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-39951
    • Availability
      Product Discontinued

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HtrA3 Antibody Summary

Immunogen
A synthetic peptide within amino acid residues 250-300 of human HtrA3 was used as immunogen.
Clonality
Polyclonal
Host
Rabbit
Gene
HTRA3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-3 ug/ml
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
Theoretical MW
49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for HtrA3 Antibody

  • EC 3.4.21
  • EC 3.4.21.-
  • EC 3.4.21.108
  • High-temperature requirement factor A3
  • HtrA serine peptidase 3
  • Pregnancy-related serine protease
  • probable serine protease HTRA3
  • Prsp
  • serine protease HTRA3
  • Tasp

Background

HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. HtrA3 has two isoforms (long and short), which are produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibits the signaling of BMP-4, -2 and TGF-beta 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurs upstream of the cell surface receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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HtrA3 NBP1-39951

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Bioinformatics

Gene Symbol HTRA3
Entrez
Uniprot