HSPA8/HSC71/Hsc70 Antibody


Western Blot: HSPA8/HSC71/Hsc70 Antibody [NBP1-51186] - Extracts from HeLa cells

Product Details

Product Discontinued
View other related HSPA8/HSC71/Hsc70 Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

HSPA8/HSC71/Hsc70 Antibody Summary

Synthetic peptide, corresponding to amino acids 211-260 of Human HSC 70.
HSC 70 (K251) pAb detects endogenous levels of HSC 70 protein.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of HSC 70 (K251) pAb in extracts from HeLa cells
Theoretical MW
70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
HSPA8/HSC71/Hsc70 Lysate (NBP2-66130)

Reactivity Notes

Cross reacts with Human, Mouse and Rat.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (approx. pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for HSPA8/HSC71/Hsc70 Antibody

  • Heat shock 70 kDa protein 8
  • heat shock 70kD protein 8
  • heat shock 70kDa protein 8
  • heat shock cognate 71 kDa protein
  • heat shock cognate protein 54
  • heat shock cognate protein, 71-kDa
  • HSC54
  • HSC70
  • HSC70heat shock 70kd protein 10
  • HSC71
  • HSP71
  • HSP73
  • HSP73constitutive heat shock protein 70
  • HSPA10
  • HSPA8
  • LAP1
  • lipopolysaccharide-associated protein 1
  • LPS-associated protein 1
  • MGC131511
  • MGC29929
  • NIP71
  • N-myristoyltransferase inhibitor protein 71


The HSP 70 family is composed of four highly conserved proteins: HSP 70, HSC 70, GRP 75 and GRP 78. These proteins serve a variety of roles: they act as molecular chaperones facilitating the assembly of multi-protein complexes, participate in the translocation of polypeptides across cell membranes and to the nucleus and aid in the proper folding of nascent polypeptide chains. All members of the family, except HSP 70, are constitutively expressed in primate cells. HSP 70 expression is strongly induced in response to heat stress. HSP 70 and HSC 70 (heat shock cognate protein 70) play key roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery and are found in both the cytosol and nucleus of mammalian cells. Both HSP 70 and HSC 70 are involved in the chaperoning of nascent polypeptide chains and in protecting cells against the accumulation of improperly folded proteins. GRP 78 is localized in the endoplasmic reticulum, where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. GRP 75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. GRP 75 and GRP 78 are unresponsive to heat stress and are induced by glucose deprivation. It has been postulated that members of the HSP 70 family act as force-generating motors, relying on the hydrolysis of ATP for their activity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Pm, Rb, Sh
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu, Rt, Ch, Dr, Pm
Applications: WB, ELISA, IHC, IHC-P
Species: Hu, Mu, Rt, Ha, Pm
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Bv, Fe, Fi, Ha, Pm
Applications: WB, B/N, Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, KO
Species: Hu, Mu
Applications: WB (-), ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu, Rt, Ch, Dr, Sh
Applications: WB, Simple Western, Flow, ICC/IF
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, IP
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, IHC, IP
Species: Hu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Species: Hu
Applications: WB, ELISA, ICC/IF
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, KD
Species: Hu, Mu, Rt, Ye, Xp(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready, Flow-IC
Species: Hu, Mu, Rt, Bv, Ch, Ha
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB

Publications for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186) (0)

There are no publications for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186) (0)

There are no reviews for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Additional HSPA8/HSC71/Hsc70 Products

Bioinformatics Tool for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186)

Discover related pathways, diseases and genes to HSPA8/HSC71/Hsc70 Antibody (NBP1-51186). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186)

Discover more about diseases related to HSPA8/HSC71/Hsc70 Antibody (NBP1-51186).

Pathways for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186)

View related products by pathway.

PTMs for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186)

Learn more about PTMs related to HSPA8/HSC71/Hsc70 Antibody (NBP1-51186).

Research Areas for HSPA8/HSC71/Hsc70 Antibody (NBP1-51186)

Find related products by research area.

Blogs on HSPA8/HSC71/Hsc70.

Chaperone Mediated Autophagy (CMA) does it all!
By Christina Towers, PhD. The degradation of cellular proteins is a critical step of both regulation and quality control and results in the turn over and recycling of critical amino acids. The two main mechanisms o...  Read full blog post.

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our HSPA8/HSC71/Hsc70 Antibody and receive a gift card or discount.


Gene Symbol HSPA8