HSP60 Recombinant Protein Summary
A recombinant protein with a His-tag corresponding to amino acids 1 to 573 of Human HSP60
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLRLPTVFRQ MRPVSRVLAP HLTRAYAKDV KFGADARALM LQGVDLLADA VAVTMGPKGR TVIIEQSWGS PKVTKDGVTV AKSIDLKDKY KNIGAKLVQD VANNTNEEAG DGTTTATVLA RSIAKEGFEK ISKGANPVEI RRGVMLAVDA VIAELKKQSK PVTTPEEIAQ VATISANGDK EIGNIISDAM KKVGRKGVIT VKDGKTLNDE LEIIEGMKFD RGYISPYFIN TSKGQKCEFQ DAYVLLSEKK ISSIQSIVPA LEIANAHRKP LVIIAEDVDG EALSTLVLNR LKVGLQVVAV KAPGFGDNRK NQLKDMAIAT GGAVFGEEGL TLNLEDVQPH DLGKVGEVIV TKDDAMLLKG KGDKAQIEKR IQEIIEQLDV TTSEYEKEKL NERLAKLSDG VAVLKVGGTS DVEVNEKKDR VTDALNATRA AVEEGIVLGG GCALLRCIPA LDSLTPANED QKIGIEIIKR TLKIPAMTIA KNAGVEGSLI VEKIMQSSSE VGYDAMAGDF VNMVEKGIID PTKVVRTALL DAAGVASLLT TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG GMF
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Liquid in 25mM Tris pH 7.5, 100mM NaCl, 5mM DTT, 10% glycerol.
The purity of this protein is > 95% by SDS-PAGE. Molecular weight is 63kDa (593aa)
Alternate Names for HSP60 Recombinant Protein
- 60 kDa chaperonin
- Chaperonin 60
- heat shock 60kD protein 1 (chaperonin)
- heat shock 60kDa protein 1 (chaperonin)
- Heat shock protein 60
- heat shock protein 65
- Mitochondrial matrix protein P1,60 kDa heat shock protein, mitochondrial
- P60 lymphocyte protein
- short heat shock protein 60 Hsp60s1
- spastic paraplegia 13 (autosomal dominant)
Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. HSP60 is the ~60kDa mammalian equivalent to GroEL of E.coli. Process of HSP60 is regulated by the cochaperonin HSP10, a single heptameric ring of ~10kD subunits that forms a complex with HSP60. HSP10 coordinates the ATPase activity of the HSP60 subunits to allow the release of bound polypeptide in a manner productive for folding. Recombinant human HSP60, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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Bioinformatics Tool for HSP60 Protein (NBC1-18372)
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