HMGB1/HMG-1 Antibody


Immunohistochemistry-Paraffin: HMGB1/HMG-1 Antibody [NBP1-50298] - Analysis of anti-HMGB1 antibody with human lung, respiratory epithelium at concentration 5 ug/ml.

Product Details

Reactivity Hu, PoSpecies Glossary
Applications WB, IHC-P
1 mg/ml

Order Details

HMGB1/HMG-1 Antibody Summary

A hMGB1/HMG 1 protein purified from porcine thymus glands.
Recognizes HMGB1/HMG 1, Mr 32kD. Species cross-reactivity: Human. Broad species cross-reactivity is expected.
Protein A purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1 M Tris-glycine, pH 7.4, 0.15 M Sodium Chloride, 30% Glycerol.
0.05% Sodium Azide
1 mg/ml
Protein A purified

Alternate Names for HMGB1/HMG-1 Antibody

  • Amphoterin
  • high mobility group box 1
  • High mobility group protein 1
  • high mobility group protein B1
  • high-mobility group (nonhistone chromosomal) protein 1
  • high-mobility group box 1
  • HMG1
  • HMG-1
  • HMG1DKFZp686A04236
  • HMG3
  • SBP-1
  • Sulfoglucuronyl carbohydrate binding protein


HMG1 and HMG2, chromatin non-histone high mobility group proteins 1 and 2, are 27 and 25 kDa members of a family of proteins containing multiple HMG-boxes, conserved domains of 80 amino acids which mediate DNA binding of many proteins. HMG box domains recognize DNA structure, such as prebent, supercoiled or four way junction DNA, and non- specific DNA sequences. Both HMG1 and HMG2 contain an N-terminal HMG box, a central HMG box, and an acidic carboxy terminus. The acidic tails of these proteins contain multiple serine residues which match the phosphorylation consensus sites of casein kinase II, and phosphorylation of this domain appears to be important for proper functioning of these proteins. HMG1/2 have been shown to facilitate the binding of various sequence-specific transcription factors to their respective DNA binding sites, such as steroid hormone receptors, p53, and Oct. HMG1/2 may serve as architectural factors that recognize and mediate DNA structural changes that accompany various events such as DNA repair, transcription and replication.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol HMGB1

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