HMGA1 Peptide



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HMGA1 Peptide Summary

Protein/Peptide Type

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.

Alternate Names for HMGA1 Peptide

  • high mobility group AT-hook 1
  • High mobility group AT-hook protein 1
  • High mobility group protein A1
  • high mobility group protein HMG-I/HMG-Y
  • High mobility group protein R
  • high-mobility group (nonhistone chromosomal) protein isoforms I and Y
  • HMGA1A
  • HMG-I(Y)
  • HMGIYMGC12816
  • HMG-R
  • MGC4242
  • MGC4854
  • nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y


Principal Names: High Mobility Group AT-Hook 1 (HMGA-1); High mobility group protein HMG-I/HMG-Y, HMG-I(Y); HMG-R; Official Gene Symbol: HMGA1 HMGA1, an 11KDa basic, DNA-binding non-histone nuclear protein, is a key member of HMGA protein family. It consists of a highly conserved AT-hook DNA-binding domain that mediates binding to AT-rich sequences in the minor groove of chromosomal DNA. It functions as architectural chromatin-binding transcription factor altering the conformation of DNA by modulating nuclear protein-DNA complexes. It is involved in many cellular processes including growth regulation, viral induction of beta-IFN gene and regulation of inducible gene transcription. It also physically interacts with transcription factors such as AP-1, Sp-1 and CAAT/enhancer binding protein-beta to modulate their ability to activate gene expression. It functions as a direct transcriptional target of c-Jun and c-Myc and is maximally expressed during embryonic development. Pathological role of HMGA1 include integration of retroviruses into chromosomes and enhancing metastasis of tumor cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Additional HMGA1 Products

Bioinformatics Tool for HMGA1 Peptide (NBP1-36744PEP)

Discover related pathways, diseases and genes to HMGA1 Peptide (NBP1-36744PEP). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for HMGA1 Peptide (NBP1-36744PEP)

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Pathways for HMGA1 Peptide (NBP1-36744PEP)

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PTMs for HMGA1 Peptide (NBP1-36744PEP)

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Research Areas for HMGA1 Peptide (NBP1-36744PEP)

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Gene Symbol HMGA1