HLA DRB1 Antibody (LN-3) [DyLight 650]

Images

 
There are currently no images for HLA-DR Antibody (NBP2-34676C).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mk, Mu(-)Species Glossary
Applications WB
Clone
LN-3
Clonality
Monoclonal
Host
Mouse

HLA DRB1 Antibody (LN-3) [DyLight 650] Summary

Immunogen
Activated human peripheral blood mononuclear cells
Localization
Cell surface
Specificity
This MAb reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
DyLight 650
Format
DyLight 650 (A=652, E=672)
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Applications/Dilutions

Dilutions
  • Western Blot
Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Alternate Names for HLA DRB1 Antibody (LN-3) [DyLight 650]

  • Clone P2-beta-3
  • DR1
  • DR-1
  • DR12
  • DR-12
  • DR13
  • DR-13
  • DR14
  • DR-14
  • DR16
  • DR-16
  • DR4
  • DR-4
  • DR5
  • DR-5
  • DR7
  • DR-7
  • DR8
  • DR-8
  • DR9
  • DR-9
  • DRB1
  • DRw10
  • DRw11
  • DRw8
  • DW2.2/DR2.2
  • FLJ75017
  • FLJ76359
  • HLA class II antigen beta chain
  • HLA class II histocompatibility antigen, DR-1 beta chain
  • HLA-DR1B
  • HLA-DRB
  • HLA-DRB1*
  • HLA-DRB2
  • HLA-DR-beta 1
  • human leucocyte antigen DRB1
  • leucocyte antigen DR beta 1 chain
  • leucocyte antigen DRB1
  • lymphocyte antigen DRB1
  • major histocompatibility complex, class II, DR beta 1
  • MHC class II antigen DRB1*1
  • MHC class II antigen DRB1*10
  • MHC class II antigen DRB1*11
  • MHC class II antigen DRB1*12
  • MHC class II antigen DRB1*13
  • MHC class II antigen DRB1*14
  • MHC class II antigen DRB1*15
  • MHC class II antigen DRB1*16
  • MHC class II antigen DRB1*3
  • MHC class II antigen DRB1*4
  • MHC class II antigen DRB1*7
  • MHC class II antigen DRB1*8
  • MHC class II antigen DRB1*9
  • MHC class II antigen HLA-DR13
  • MHC class II HLA-DR beta 1 chain
  • MHC class II HLA-DR-beta cell surface glycoprotein
  • MHC class II HLA-DRw10-beta
  • SS1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

H00003126-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
NBP2-29931
Species: Hu
Applications: WB, Flow, IHC-P
NB100-64775
Species: Hu, Bb, Bv, Pm
Applications: ELISA, Flow, Func, ICC/IF, IHC, IHC-Fr, IP
H00003115-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, IP
NBP1-84549
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NB120-6405
Species: Rt
Applications: B/N, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IP, Flow-IC
AF347
Species: Hu
Applications: WB, IHC, Neut
H00003120-M01
Species: Hu
Applications: WB, ELISA
NBP2-32001
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-84550
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-23210
Species: Hu
H00001810-B01P
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
H00003125-B02P
Species: Hu
Applications: WB, ELISA, Flow
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP2-14093
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-34676C
Species: Hu, Mk, Mu(-)
Applications: WB

Publications for HLA-DR Antibody (NBP2-34676C) (0)

There are no publications for HLA-DR Antibody (NBP2-34676C).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for HLA-DR Antibody (NBP2-34676C) (0)

There are no reviews for HLA-DR Antibody (NBP2-34676C). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for HLA-DR Antibody (NBP2-34676C). (Showing 1 - 1 of 1 FAQ).

  1. We are interested in custom labeling our antibodies to be able to integrate new markers into already existing multicolor FACS panels. We would be glad to receive pricing and general order information for anti-HLA-DRB1 and anti-HLA-DRB5. To estimate expenses for future antibody labeling orders it would be helpful to know on what basis (amount, type, etc.) the price is going to be calculated. Right now the antibodies are still in mouse ascites. Would it be possible to integrate the elution of the antibodies from the ascites before labeling as part of the service agreement?
    • While we do not generally do this kind of custom purification unless it is for very large amounts of antibody, we do have a number of kits available that may be of use to you. Since an antibody that is still in ascites can not be labeled, it will need to be purified. A list of our kits available for this can be found at the following link: AbSelect. Once the antibodies are purified, they can be labeled with any number of different colors. A list of these kits for labeling can be found at the following link: Lightning-Link.

Secondary Antibodies

 

Isotype Controls

Additional HLA DRB1 Antibody (LN-3) [DyLight 650] Products

Related Products by Gene

Diseases for HLA-DR Antibody (NBP2-34676C)

Discover more about diseases related to HLA-DR Antibody (NBP2-34676C).
 

Pathways for HLA-DR Antibody (NBP2-34676C)

View related products by pathway.

PTMs for HLA-DR Antibody (NBP2-34676C)

Learn more about PTMs related to HLA-DR Antibody (NBP2-34676C).
 

Research Areas for HLA-DR Antibody (NBP2-34676C)

Find related products by research area.

Blogs on HLA DRB1

There are no specific blogs for HLA DRB1, but you can read our latest blog posts.

Contact Information

Product PDFs

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP2-34676C below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought