Histone Deacetylase 4/HDAC4 Antibody

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Immunohistochemistry-Paraffin: Histone Deacetylase 4/HDAC4 Antibody [NBP1-50208] - Analysis of anti-HDAC4 antibody with human skin at dilution 1:50.

Order Details


    • Catalog Number
      NBP1-50208
    • Availability
      Product Discontinued

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Histone Deacetylase 4/HDAC4 Antibody Summary

Immunogen
Recombinant human HDAC4 (partial), N-terminal
Specificity
HDAC4
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HDAC4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 2 ug/ml
  • Immunohistochemistry-Paraffin 1:50
  • Immunofluorescence 1:10 - 1:500

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 50% Glycerol
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Histone Deacetylase 4/HDAC4 Antibody

  • HA6116
  • HD4EC 3.5.1.98
  • HDAC4
  • HDAC-A
  • HDACABDMR
  • Histone Deacetylase 4
  • histone deacetylase A
  • KIAA0288AHO3

Background

HDAC4 is a 140 kD class II histone deacetylase similar to the yeast HDA1 protein. This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues. HDAC activity has been associated with transcriptional repression and nucleosomal condensation. HDAC4 uses active nuclear export to shuttle between the nucleus and the cytoplasm. HDAC4 is modified by phosphorylation by CaM kinase I or IV. HDAC4 has been reported to interact with 14-3-3 in the cytoplasm and MEF2A, HDAC3, NcoR and SMRT in the nucleus. The Poly6077 antibody has been shown to be useful for the detection of human (Western blotting and immunofluorescence) and mouse (Western blotting; immunofluorescence not tested) HDAC4 protein. Associates with 14-3-3 in cytoplasm and MEF2A in nucleus, interacts with HDAC3, NcoR, SMART

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Additional Histone Deacetylase 4/HDAC4 Products

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Bioinformatics

Gene Symbol HDAC4
Entrez
Uniprot