Histone Deacetylase 4/HDAC4 Antibody

Images

 
Western Blot: Histone Deacetylase 4/HDAC4 Antibody [H00009759-D01P] - Analysis of HDAC4 expression in transfected 293T cell line by HDAC4 polyclonal antibody.Lane 1: HDAC4 transfected lysate(106.40 KDa).Lane 2: ...read more

Order Details


    • Catalog Number
      H00009759-D01P
    • Availability
      Product Discontinued

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Histone Deacetylase 4/HDAC4 Antibody Summary

Immunogen
HDAC4 (AAH39904.1, 1 a.a. ~ 972 a.a) full-length human protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HDAC4
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
This antibody is useful for Western Blot

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Histone Deacetylase 4/HDAC4 Antibody

  • HA6116
  • HD4EC 3.5.1.98
  • HDAC4
  • HDAC-A
  • HDACABDMR
  • Histone Deacetylase 4
  • histone deacetylase A
  • KIAA0288AHO3

Background

Histone deacetylase 4 belongs to the histone deacetylase family type 2 which actively deacetylate the 4 core Histones. HDAC4 possesses two repression domains, one composed of the N-terminal 208 residues and the other consist of a deacetylase domain (1). The N-term will interact with the MADX-box of MEFC2 to negatively regulate expression. Additionally, the deacetylase activity of HDAC4 is subject to negative regulation by its N-terminal domain (2). HDAC4 is also implicated in the regulation of muscle differentiation. During muscle differentiation, HDC4 is shuttled between nuclear and cytoplasmic compartments. Phosphorylation by CAMK4 at S246, S467 and S632 can control HDAC4 subcellular localization (3-4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Histone Deacetylase 4/HDAC4 Antibody (H00009759-D01P) (0)

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Video Protocols

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Secondary Antibodies

 

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Additional Histone Deacetylase 4/HDAC4 Products

Bioinformatics Tool for Histone Deacetylase 4/HDAC4 Antibody (H00009759-D01P)

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Bioinformatics

Gene Symbol HDAC4
Entrez
Uniprot