Histone Deacetylase 4/HDAC4 Antibody (7B2)

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Western Blot: Histone Deacetylase 4/HDAC4 Antibody (7B2) [NBP1-51594] - Western blot analysis using HDAC4 mouse mAb against Hela (1), Jurkat (2) cell lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
7B2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Histone Deacetylase 4/HDAC4 Antibody (7B2) Summary

Immunogen
Purified recombinant fragment of human HDAC4 expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HDAC4
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
Theoretical MW
119 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for Histone Deacetylase 4/HDAC4 Antibody (7B2)

  • HA6116
  • HD4EC 3.5.1.98
  • HDAC4
  • HDAC-A
  • HDACABDMR
  • Histone Deacetylase 4
  • histone deacetylase A
  • KIAA0288AHO3

Background

HDAC4 is a 140 kD class II histone deacetylase similar to the yeast HDA1 protein. This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues. HDAC activity has been associated with transcriptional repression and nucleosomal condensation. HDAC4 uses active nuclear export to shuttle between the nucleus and the cytoplasm. HDAC4 is modified by phosphorylation by CaM kinase I or IV. HDAC4 has been reported to interact with 14-3-3 in the cytoplasm and MEF2A, HDAC3, NcoR and SMRT in the nucleus. The Poly6077 antibody has been shown to be useful for the detection of human (Western blotting and immunofluorescence) and mouse (Western blotting; immunofluorescence not tested) HDAC4 protein. Associates with 14-3-3 in cytoplasm and MEF2A in nucleus, interacts with HDAC3, NcoR, SMART

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HDAC4
Entrez