Histamine N-Methyltransferase/HNMT Overexpression Lysate (Denatured)

Images

 
Lane 1: HNMT transfected lysate (32.23 KDa) Lane 2: Non-transfected lysate.
HNMT transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

Histamine N-Methyltransferase/HNMT Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-HNMT full-length
Gene
HNMT

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Histamine N-Methyltransferase/HNMT

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-HNMT antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Histamine N-Methyltransferase/HNMT Overexpression Lysate (Denatured)

  • EC 2.1.1.8
  • Histamine NMethyltransferase
  • Histamine N-Methyltransferase
  • HMT
  • HNMT
  • HNMT-S1
  • HNMT-S2

Background

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Publications for Histamine N-Methyltransferase/HNMT Lysate (H00003176-T01) (0)

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Video Protocols

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Bioinformatics

Gene Symbol HNMT
Entrez