HIF-2 alpha/EPAS1 RNAi


Immunocytochemistry/ Immunofluorescence: HIF-2 alpha RNAi [H00002034-R01] - left - control and right - gene expression after siRNA treatment. Image from verified customer review.

Product Details

Reactivity HuSpecies Glossary
Concentration is not relevant for this product. Please see the protocols for proper use of this product.

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HIF-2 alpha/EPAS1 RNAi Summary

endothelial PAS domain protein 1 (EPAS1), mRNA

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.


Reviewed Applications
Read 1 Review rated 5
H00002034-R01 in the following application:

Read Publications using H00002034-R01.


This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HIF-2 alpha/EPAS1 RNAi

  • Basic-helix-loop-helix-PAS protein MOP2
  • BHLHE73
  • bHLHe73ECYT4
  • Class E basic helix-loop-helix protein 73
  • endothelial PAS domain protein 1
  • endothelial PAS domain-containing protein 1
  • EPAS1
  • EPAS-1
  • HIF-1alpha-like factor
  • HIF2 alpha
  • HIF-2 alpha
  • hif2a angiogenesis
  • HIF2A
  • HIF2AHIF-2-alpha
  • HLF
  • HLFHIF-1-alpha-like factor
  • hypoxia-inducible factor 2 alpha
  • Hypoxia-inducible factor 2-alpha
  • Member of PAS protein 2
  • MOP2
  • MOP2HIF2-alpha
  • PASD2PAS domain-containing protein 2


Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene. The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo. Chimera RNAi has many advantages over the conventional siRNAs. First, it has been demonstrated to have reliable knock-down for over 10,000 human genes. Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence. Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected. Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Publications for HIF-2 alpha/EPAS1 RNAi (H00002034-R01)(3)

Reviews for HIF-2 alpha/EPAS1 RNAi (H00002034-R01) (1) 51

Average Rating: 5
(Based on 1 reviews)
We have 1 review tested in 1 species: Human.
We have 1 review tested in 1 application: Flow.

Reviews using H00002034-R01:
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Images Ratings Applications Species Date Details
Flow Cytometry HIF-2 alpha/EPAS1 H00002034-R01
reviewed by:
Flow Human 10/06/2014


ApplicationFlow Cytometry
Sample Testedsome cells
CommentsThe gene silencing effect is excellent. But sometimes it needs efficient quantity.


CommentsThe gene silencing effect is excellent. But sometimes it needs efficient quantity.

Product General Protocols

View specific protocols for HIF-2 alpha/EPAS1 RNAi (H00002034-R01): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for HIF-2 alpha/EPAS1 RNAi (H00002034-R01) (0)

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Blogs on HIF-2 alpha/EPAS1.

HIF-2 alpha: HIF1A's Homologue with Similar and Divergent Functions
HIF-2 alpha is a member of the heterodimeric hypoxia-inducible factors/HIFs family (HIF-1, HIF-2, and HIF-3) which contains a common beta subunit but differ in their alpha subunits. Also called as EPAS1 or Mop2, HIF-2 alpha regulates cellular adapt...  Read full blog post.

HIF-2 alpha, Tumor Suppression and Cell Survival
HIF-2 alpha is one subunit within the HIF-2 nuclear protein that regulates cellular responses to hypoxia (low oxygen tension conditions). Hydroxylation post-translational modifications on particular HIF residues target them for degradation. Luo, et al...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol EPAS1

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