HGK/MAP4K4 Antibody (SP177)

Images

 
Immunohistochemistry-Paraffin: MAP4K4 Antibody (SP177) [NBP2-21767] - Human prostate adenocarcinoma.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clone
SP177
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

HGK/MAP4K4 Antibody (SP177) Summary

Immunogen
Synthetic peptide derived from the C-terminus of human MAP4K4 protein.
Localization
Cytoplasm
Clonality
Monoclonal
Host
Rabbit
Gene
MAP4K4
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
Theoretical MW
142 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Tested in Human. Based on sequence identity cross reactivity is expected with Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.6) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Protein G purified

Alternate Names for HGK/MAP4K4 Antibody (SP177)

  • EC 2.7.11
  • EC 2.7.11.1
  • FLH21957
  • FLJ10410
  • hepatocyte progenitor kinase-like/germinal center kinase-like kinase
  • HGK
  • HGKFLJ20373
  • HPK/GCK-like kinase HGK
  • KIAA0687
  • MAP4K4
  • MAPK/ERK kinase kinase kinase 4
  • MEK kinase kinase 4
  • MEKKK 4
  • MEKKK4
  • mitogen-activated protein kinase kinase kinase kinase 4
  • Nck-interacting kinase
  • NIKFLJ90111

Background

Mitogen-activated protein kinase kinase kinase 4 (MAP4K4) is a member of stress activated MAP kinase signaling pathway. It directly phosphorylates and activates the c-Jun N-terminal kinase (JNK) and p38 families of MAP kinases in response to various stimulating factors. It involves the mediation of TNF-alpha signaling pathway. MAP4K4 is overexpressed in many types of human cancer such as carcinoma of prostate, ovarian, liver, and pancreas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MAP4K4
Entrez