HGF Recombinant Protein


There are currently no images for HGF Protein (NBP1-43184).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity HuSpecies Glossary
Applications IA
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

HGF Recombinant Protein Summary

A recombinant protein corresponding to HGF.
Insect cells infected with baculovirus: amino acids 1-728 of human HGF (accession # M73239).
Details of Functionality
This recombinant human HGF has been tested in a bioassay of dose-dependent stimulation of 4MBr5 cell proliferation. The ED50 for this is typically 50 ng/ml, corresponding to a specific activity of 2.0 x 10^4U/mg.
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid; phosphate buffered saline, pH 7.2, 150 mM NaCl, with 0.1% BSA as a stabilizer. 0.22 uM filtered.
0.09% Sodium Azide


  • Immunoassay

Reactivity Notes

This protein was made to the human sequence.

Alternate Names for HGF Recombinant Protein

  • deafness, autosomal recessive 39
  • DFNB39
  • EC 3.4.21
  • EC
  • fibroblast-derived tumor cytotoxic factor
  • F-TCF
  • hepatocyte growth factor (hepapoietin A; scatter factor)
  • Hepatopoeitin-A
  • Hepatopoietin A
  • HGFB
  • HPTAhepatocyte growth factor
  • lung fibroblast-derived mitogen
  • Scatter factor
  • SF
  • SFhepatopoeitin-A


Hepatocyte Growth Factor (HGF), also known as Hepatopoietin A and Scatter Factor, was originally identified based on its mitogenic activity for hepatocytes. Plasma from patients with hepatic failure was found to contain a factor that stimulates the growth of rat hepatocytes in primary culture. This plasma-derived HGF was purified and found to have multiple forms with molecular weights between 76 kD and 92 kD. Mature HGF consists of 2 disulfide-linked chains, heavy and light, with molecular weights of 54-65 kD and 31.5-34.5 kD, respectively. The heavy and light chains are encoded by the same mRNA, which by translation yields a biologically inactive single chain pro-peptide. The pro-peptide is cleaved by an extracellular serum serine protease to form the bioactive disulfide-linked alpha and beta chain heterodimeric HGF. HGF has also been described as Scatter Factor, based on its capacity to stimulate the dissociation and scattering of epithelial cells. The sequence of HGF has about 35% identity to that of plasminogen and the putative cleavage site of HGF is identical to that of plasminogen. The HGF receptor gene, the MET oncogene, is located on 7q, along with the HGF gene. An increase in the copy number of chromosome 7 is one of the most common chromosome abnormalities observed in human malignant gliomas.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, Flow, IHC, Block
Species: Hu
Applications: WB, DB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC, ICFlow
Species: Hu, Rt, Ca, Mk
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu
Applications: WB, Simple Western
Species: Hu
Applications: WB, Simple Western, ICC
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P

Publications for HGF Protein (NBP1-43184) (0)

There are no publications for HGF Protein (NBP1-43184).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for HGF Protein (NBP1-43184) (0)

There are no reviews for HGF Protein (NBP1-43184). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

FAQs for HGF Protein (NBP1-43184) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional HGF Recombinant Protein Products

Related Products by Gene

Bioinformatics Tool for HGF Protein (NBP1-43184)

Discover related pathways, diseases and genes to HGF Protein (NBP1-43184). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for HGF Protein (NBP1-43184)

Discover more about diseases related to HGF Protein (NBP1-43184).

Pathways for HGF Protein (NBP1-43184)

View related products by pathway.

PTMs for HGF Protein (NBP1-43184)

Learn more about PTMs related to HGF Protein (NBP1-43184).

Research Areas for HGF Protein (NBP1-43184)

Find related products by research area.

Blogs on HGF.

VEGFR-2 - A highly active kinase
VEGFR-2 is a family member of the vascular endothelial growth factor (VEGF) family of membrane receptor tyrosine kinases. It is a key regulator of the process of angiogenesis that takes place during fundamental developmental processes such as embry...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol HGF

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-43184 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought

HGF Antibody
HGF Antibody