Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [DyLight 680]

• Reactivity: Hu
• Applications: IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 680

Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [DyLight 680] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HS2ST1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [DyLight 680]

• 2OST
• 2-O-sulfotransferase
• EC 2.8.2
• EC 2.8.2.-
• FLJ11317
• heparan sulfate 2-O-sulfotransferase 1
• HS2ST
• HS2ST1
• KIAA0448dJ604K5.2
• MGC131986

Background

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes heparan sulfate 2-O-sulfotransferase, a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HS2ST1