Recombinant Human HDGF Protein

SDS-Page: Recombinant Human HDGF Protein [NBP1-30260] - HDGF, 11.5 kDa (100aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human HDGF Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 1-100 of Human HDGF
  
  

  Source: E.coli

  Amino Acid Sequence: MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: HDGF
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 11.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH7.5), 1 mM DTT, 10% glycerol, 1 mM EDTA
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human HDGF Protein

• FLJ96580
• HDGF
• hepatoma-derived growth factor (high-mobility group protein 1-like)
• hepatoma-derived growth factor
• High mobility group protein 1-like 2
• HMG-1L2
• HMG1L2DKFZp686J1764
• HuHGF

Background

Hepatoma-derived growth factor isoform a, also known as HDGF, belongs to the hepatoma-derived growth factor family. HDGF was originally identified as a secreted mitogen from the human hepatoma cell line Huh-7. This nuclear targeted vascular smooth muscle cell mitogen is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. Recombinant human HDGF was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: HDGF