HDAC6 Antibody (EPR1698(2))

Product Discontinued

HDAC6 Antibody (EPR1698(2)) Summary

• Immunogen: A synthetic peptide corresponding to residues near the N-terminus in human Histone Deacetylase 6 was used as an immunogen.
• Clonality: Monoclonal
• Host: Rabbit
• Gene: HDAC6
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:500 - 1000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 100
  • Immunoprecipitation 1:10 - 100
  • Western Blot 1:10000 - 50000

Reactivity Notes

Human. Species cross-reactivity is based on Western Blot analysis.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 49% PBS, 0.05% BSA and 50% Glycerol
• Preservative: 0.01% Sodium Azide
• Purity: Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for HDAC6 Antibody (EPR1698(2))

• CPBHM
• EC 3.5.1.98
• FLJ16239
• HD6
• HD6FLJ16239
• HDAC6
• Histone Deacetylase 6
• JM21
• KIAA0901
• PPP1R90

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone Deacetylase 6 belongs to the class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains, which appear to function independently of each other. Histone Deacetylase 6 possesses histone deacetylase activity and represses transcription (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HDAC6
• Uniprot:
  • Q9UBN7(Human)