HDAC1 Antibody

Images

 
Western Blot: HDAC1 Antibody [NBP1-44097] - Lane 1: mouse brain extract. Lane 2: mouse brain extract blocked with peptide. Load: 5 ug per lane. Primary antibody: HDAC1 antibody at 1ug/mL for overnight at 4C. Secondary ...read more

Product Details

Summary
Product Discontinued
View other related HDAC1 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-44097
    • Availability
      Product Discontinued

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HDAC1 Antibody Summary

Immunogen
A synthetic peptide corresponding to a region of HDAC1 between residues 400 -500.
Specificity
This antibody is specific to a region of HDAC1 between residues 400 -500.
Clonality
Polyclonal
Host
Rabbit
Gene
HDAC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
Publications
Read Publication using NBP1-44097.

Reactivity Notes

This antibody is reactive in Human, Mouse, Rat and Primate

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 50% (v/v) Glycerol
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute with 185 ml of water to desired concentration and for immediate usage.

Alternate Names for HDAC1 Antibody

  • EC 3.5.1.98
  • GON-10
  • HD1DKFZp686H12203
  • histone deacetylase 1
  • reduced potassium dependency, yeast homolog-like 1
  • RPD3L1RPD3

Background

HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HDAC1 Antibody (NBP1-44097)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for HDAC1 Antibody (NBP1-44097) (0)

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Secondary Antibodies

 

Isotype Controls

Additional HDAC1 Products

Bioinformatics Tool for HDAC1 Antibody (NBP1-44097)

Discover related pathways, diseases and genes to HDAC1 Antibody (NBP1-44097). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for HDAC1 Antibody (NBP1-44097)

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PTMs for HDAC1 Antibody (NBP1-44097)

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Research Areas for HDAC1 Antibody (NBP1-44097)

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Blogs on HDAC1.

The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies
Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...  Read full blog post.

The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...  Read full blog post.

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Bioinformatics

Gene Symbol HDAC1
Entrez
Uniprot