GTF2IRD1 Antibody

Images

 
Western Blot: GTF2IRD1 Antibody [NB100-92409] - Analysis of GTF2IRD1 antibody at 1:500 dilution. Lane 1 - HEK293T whole cell lysate, Lane 2 - Raw264.7 whole cell lysate, Lane 3 - H9C2 whole cell lysate.

Product Details

Summary
Product Discontinued
View other related GTF2IRD1 Primary Antibodies

Order Details


    • Catalog Number
      NB100-92409
    • Availability
      Product Discontinued

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GTF2IRD1 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 63-112 of Human WBSCR11.
Specificity
GTF2IRD1 antibody detects endogenous levels of human GTF2I repeat domain-containing protein.
Clonality
Polyclonal
Host
Rabbit
Gene
GTF2IRD1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Theoretical MW
106 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
GTF2IRD1 Lysate (NBL1-11393)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GTF2IRD1 Antibody

  • BEN
  • CREAM1
  • general transcription factor II-I repeat domain-containing protein 1
  • General transcription factor III
  • GTF2I repeat domain containing 1
  • GTF2I repeat domain-containing protein 1
  • GTF3GTF2I repeat domain-containing 1
  • hMusTRD1alpha1
  • muscle TFII-I repeat domain-containing protein 1 alpha 1
  • Muscle TFII-I repeat domain-containing protein 1
  • MusTRD1
  • MusTRD1/BEN
  • MUSTRD1general transcription factor 3
  • RBAP2WBSCR12binding factor for early enhancer
  • Slow-muscle-fiber enhancer-binding protein
  • USE B1-binding protein
  • WBS
  • WBSCR11
  • Williams-Beuren syndrome chromosomal region 11 protein
  • Williams-Beuren syndrome chromosomal region 12 protein
  • Williams-Beuren syndrome chromosome region 11

Background

Williams-Beuren syndrome (WBS) is a developmental disorder caused by the hemizygous microdeletion on chromosome 7q11.23. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits. The physical traits associated with WBS include facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities. Mild retardation, a weakness in visual-spatial skills, anxiety and a short attention span are typical cognitive and behavioral traits of WBS patients. The WBSCR11 gene is located within the WBS deletion and may contribute to the developmental symptoms found in WBS because of a loss of the encoded transcription factor. WBSCR11 is also designated GRF2IRD1, GTF3, Cream1 and MusTRD1 in human and BEN in mouse, due to slight differences in gene structure. WBSCR11 is expressed in all adult tissues as several variants and has discrete spatial and temporal expression during embryogenesis. The amino-terminus of WBSCR11 interacts with transcriptional machinery proteins, while the carboxy-terminus has been shown to bind the retinoblastoma protein to possibly regulate the cell cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GTF2IRD1
Entrez
Uniprot