GSK-3 alpha Antibody (SBGSK3a2) [HRP]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-28583
    • Availability
      Product Discontinued

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GSK-3 alpha Antibody (SBGSK3a2) [HRP] Summary

Immunogen
The immunogen is a peptide made to the amino acid region GSK3 alpha
Specificity
Human, mouse and rat GSK-3 alpha
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GSK3A
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:5000-1:10000
Readout System

Reactivity Notes

Mouse, Human and Rat. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Stock solution in 50% Glycerol/50% PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A or G purified

Alternate Names for GSK-3 alpha Antibody (SBGSK3a2) [HRP]

  • DKFZp686D0638
  • EC 2.7.11
  • EC 2.7.11.26
  • glycogen synthase kinase 3 alpha
  • glycogen synthase kinase-3 alpha
  • GSK3 alpha
  • GSK-3 alpha
  • GSK3A

Background

Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 alpha and GSK-3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics Tool for GSK-3 alpha Antibody (NBP1-28583)

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Bioinformatics

Gene Symbol GSK3A
Entrez