GRTP1 Antibody

Images

 
Western Blot: GRTP1 Antibody [NBP1-76900] - K562 cell lysate with GRTP1 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: GRTP1 Antibody [NBP1-76900] - Immunofluorescence of GRTP1 in K562 cells with GRTP1 antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: GRTP1 Antibody [NBP1-76900] - K562 cells with GRTP1 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

GRTP1 Antibody Summary

Immunogen
Antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human GRTP1. The immunogen is located within the first 50 amino acids of GRTP1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRTP1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Control Peptide
GRTP1 Peptide (NBP1-76900PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GRTP1 Antibody

  • FLJ22474
  • growth hormone regulated TBC protein 1
  • growth hormone-regulated TBC protein 1
  • MGC138328
  • TBC1 domain family member 6
  • TBC1 domain family, member 6
  • TBC1D6MGC138330

Background

Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Array Products

Array NBP1-76900

Bioinformatics Tool for GRTP1 Antibody (NBP1-76900)

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Diseases for GRTP1 Antibody (NBP1-76900)

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Bioinformatics

Gene Symbol GRTP1
Uniprot