Recombinant Chicken Growth Hormone Protein

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99175
    • Availability
      Product Discontinued

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Recombinant Chicken Growth Hormone Protein Summary

Description
A recombinant protein corresponding to 191 amino acids of Chicken Growth Hormone

Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Thr-Phe-Pro-Ala
Preparation
Method
>99% SDS-PAGE
Details of Functionality
Biological Activity: GH Chicken Recombinantis fully biologically active in homologous assays and in PDF-P1 3B9 cells stably transfected with rabbit GH receptors.
Protein/Peptide Type
Recombinant Protein
Gene
GH1
Purity
>90% SDS-PAGE

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Concentration
Lyoph
Purity
>90% SDS-PAGE
Reconstitution Instructions
Centrifuge prior to opening. Reconstitute with sterilized deionized water or 0.4% NaHCO3 (pH 8-9) to a final concentration of at least 0.1 mg/ml.

Notes

The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for Recombinant Chicken Growth Hormone Protein

  • GH1
  • GHIGHD1B
  • GHNGrowth hormone
  • GH-Nsomatotropin
  • growth hormone 1Pituitary growth hormone
  • Growth Hormone
  • hGH-N
  • Somatotropin

Background

GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Growth Hormone Chicken Recombinant (cGH) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids with an additional Ala at its N-terminus and having a molecular mass of 22255 Dalton. GH Chicken recombinant is purified by proprietary chromatographic techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Blogs on Growth Hormone.

Growth hormone (GH, somatotropin, hGH, pituitary growth hormone)
GH is a member of the large family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. Additionally, GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic...  Read full blog post.

Somatostatin Receptor 2: Treating Patients Who Cannot Stop Growing
Acromegaly is a rare life-shortening disease caused by elevated levels of growth hormone (GH) secreted by a tumor on the pituitary gland. Treatments include somatostatin analogs, which activate somatostatin receptor 2 (SSTR2), reducing GH secretion an...  Read full blog post.

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Bioinformatics

Gene Symbol GH1
Entrez