GRO2 Antibody

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA, Neut
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

GRO2 Antibody Summary

Immunogen
E. coli-expressed recombinant mouse MIP-2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CXCL2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Neutralization
Application Notes
Western blot analysis (0.5-1 ug/ml) and Neutralization (2-10 ug/ml). However, the optimal conditions should be determined individually.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 1.0% BSA and 50% Glycerol
Preservative
0.02% Thimerosal
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GRO2 Antibody

  • chemokine (C-X-C motif) ligand 2
  • CINC-2a
  • GRO2 oncogene
  • GRO2MIP2
  • GROb
  • gro-beta
  • Growth-regulated protein beta
  • Macrophage inflammatory protein 2-alpha
  • melanoma growth stimulatory activity beta
  • MGSA beta
  • MGSA-b
  • MIP-2a
  • MIP2AC-X-C motif chemokine 2
  • SCYB2MIP2-alpha

Background

MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD-5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CXCL2
Entrez
Uniprot