GRO2 Antibody Summary
E. coli-expressed recombinant mouse MIP-2.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
PBS, pH 7.2, containing 50% glycerol, 1% BSA
Immunogen affinity purified
- Western Blot 0.5-1 ug/ml
- Blocking/Neutralizing 2-10 ug/ml
- ELISA 1:100-1:2000
Alternate Names for GRO2 Antibody
- chemokine (C-X-C motif) ligand 2
- GRO2 oncogene
- Growth-regulated protein beta
- Macrophage inflammatory protein 2-alpha
- melanoma growth stimulatory activity beta
- MGSA beta
- MIP2AC-X-C motif chemokine 2
MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD-5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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