Recombinant Mouse GRO alpha Protein

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Mouse GRO alpha Protein Summary

Description
A recombinant protein with a His-tag corresponding to amino acids 25 to 96 of Mouse GRO alpha

Source: E. coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAPIAN ELRCQCLQTM AGIHLKNIQS LKVLPSGPHC TQTEVIATLK NGREACLDPE APLVQKIVQK MLKGVPK
Preparation
Method
E.coli
Protein/Peptide Type
Recombinant Protein
Gene
CXCL1
Purity
>90%, by SDS-PAGE

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Liquid. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl,
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Application Notes
The purity of this protein is > 90% by SDS-PAGE. Molecular weight is 10.5 kDa(97aa), confirmed by MALDI-TOF
Theoretical MW
10.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse

Alternate Names for Recombinant Mouse GRO alpha Protein

  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • fibroblast secretory protein
  • GRO
  • GRO1 oncogene (melanoma growth stimulating activity, alpha)
  • GRO1GRO1 oncogene (melanoma growth-stimulating activity)
  • GROa
  • GRO-alpha(1-73)
  • melanoma growth stimulatory activity alpha
  • Melanoma growth stimulatory activity
  • MGSA alpha
  • MGSA-a
  • MGSAgrowth-regulated alpha protein
  • NAP-3C-X-C motif chemokine 1
  • Neutrophil-activating protein 3
  • SCYB1FSP

Background

CXCL1, also known as GROA or GRO-alpha, is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer. Recombinant mouse CXCL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CXCL1

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