GRO alpha Antibody

Images

 
Western Blot: GRO alpha Antibody [NBP2-16748] - Western Blot analysis of CXCL1 expression in transfected 293T cell line by CXCL1 polyclonal antibody. A: Non-transfected lysate. B: CXCL1 transfected lysate. 15% SDS PAGE ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

GRO alpha Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GRO alpha. The exact sequence is proprietary.
Localization
Secreted
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CXCL1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
11 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GRO alpha Antibody

  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • fibroblast secretory protein
  • GRO
  • GRO1 oncogene (melanoma growth stimulating activity, alpha)
  • GRO1GRO1 oncogene (melanoma growth-stimulating activity)
  • GROa
  • GRO-alpha(1-73)
  • melanoma growth stimulatory activity alpha
  • Melanoma growth stimulatory activity
  • MGSA alpha
  • MGSA-a
  • MGSAgrowth-regulated alpha protein
  • NAP-3C-X-C motif chemokine 1
  • Neutrophil-activating protein 3
  • SCYB1FSP

Background

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CXCL1
Uniprot