GRO alpha Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

GRO alpha Antibody Summary

Immunogen
Peptide with sequence C-EKMLNSDKSN corresponding to C-Terminus according to NP_001502.1.
Epitope
C-EKMLNSDKSN
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CXCL1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:2000
Application Notes
WB: Not yet tested - Our standard WB protocol would not expect to reliably detect proteins as small as the calculated size of 11.3 kDa band according to NP_001502.1.
Publications
Read Publication using NBP1-52142.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for GRO alpha Antibody

  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • fibroblast secretory protein
  • GRO
  • GRO1 oncogene (melanoma growth stimulating activity, alpha)
  • GRO1GRO1 oncogene (melanoma growth-stimulating activity)
  • GROa
  • GRO-alpha(1-73)
  • melanoma growth stimulatory activity alpha
  • Melanoma growth stimulatory activity
  • MGSA alpha
  • MGSA-a
  • MGSAgrowth-regulated alpha protein
  • NAP-3C-X-C motif chemokine 1
  • Neutrophil-activating protein 3
  • SCYB1FSP

Background

The GRO gene was originally identified by subtractive hybridization studies between normal and tumorigenic Chinese hamster embryo fibroblasts. The hamster cDNA was cloned and used as a probe for cloning of the human GRO cDNA. The GROalpha gene initially cloned from T24 cells and the gene in melanoma cells encoding melanoma growth stimulating protein (MGSA) are identical. Human cells contain three closely related, but distinct GRO genes: GRO alpha, GRO beta, and GRO gamma. GRO beta and GRO gamma share 93% and 82% identity, respectively, with GRO alpha at the nucleotide level. GROs are members of the chemokine alpha family that is characterized by the separation with one amino acid of the first two cysteine residues, C-X-C, in the amino acid sequence. The GRO gene has been mapped to chromosome 4q21. In normal cells, human mRNA GRO expression is found in foreskin fibroblasts, synovial fibroblasts, chondrocytes and osteocytes. Additionally, GRO mRNA has been detected in mammary fibroblasts, mammary epithelial cells, endothelial cells, activated monocytes, macrophages, and neutrophils. Characterization of the GROalpha receptor indicates the presence of low and high affinity receptors on human neutrophils

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GRO alpha Antibody (NBP1-52142)(1)

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Bioinformatics

Gene Symbol CXCL1
Entrez
Uniprot