GRASP65 Antibody (Poly6210)

Product Discontinued

GRASP65 Antibody (Poly6210) Summary

• Immunogen: Recombinant (partial)
• Specificity: GRASP65
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GORASP1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:400
• Application Notes: Immunofluorescence staining, suggested working dilution(s): 1:400 dilution.
• Control:

  GRASP65 Overexpression Lysate

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A or G purified

Alternate Names for GRASP65 Antibody (Poly6210)

• Golgi peripheral membrane protein p65
• Golgi phosphoprotein 5MGC118897
• golgi reassembly stacking protein 1, 65kDa
• Golgi reassembly-stacking protein 1
• Golgi reassembly-stacking protein of 65 kDa
• GRASP65MGC118894
• P6565 kDa

Background

GRASP65 (golgi reassembly stacking protein 1, Golgi peripheral membrane protein p65, reassembly and stacking protein p65) is a 65 kD Golgi stacking protein. Alternatively spliced transcripts of GRASP65 have been identified. This protein is thought to play a role in establishing the stacked structure of the Golgi cisternae allowing sorting and modification of proteins exported from the endoplasmic reticulum. GRASP65 is cleaved by caspase-3 during apoptosis and can be partitioned by fragmentation and dispersal during entry into mitosis. GRASP65 is modified by phosphorylation (polo-like kinase-1 and cdc2-cyclin B). This protein has been shown to form a complex with the Golgi matrix protein GOLGA2; this complex then interacts with the vesicle docking protein p115,and tethering factor GM130.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GORASP1
• Entrez:
  • 64689(Human)
• Uniprot:
  • Q9BQQ3(Human)