GRASP1 Antibody - Azide Free

Western Blot: General Receptor for phosphoinositides 1 Antibody [NB300-310] - Rat cerebellar lysate showing the specific immunolabeling of the ~95k GRASP protein, using NB300-310.

• Reactivity: Mu, Rt, Hu, Bv, Ca
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide Free

GRASP1 Antibody - Azide Free Summary

• Description: Novus Biologicals Rabbit GRASP1 Antibody - Azide Free (NB300-310) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # Q9JHZ4
• Specificity: Specific for endogenous levels of the ~95 kDa GRASP1 protein.
• Predicted Species: Human (100%), Canine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GRIPAP1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Theoretical MW: 95 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

It is anticipated that the antibody will react with bovine, canine, human and mouse based on the fact that these species have 100% homology with the amino acid sequence used as antigen.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for GRASP1 Antibody - Azide Free

• DKFZp434P0630
• GRASP1
• GRASP-1MGC126595
• GRIP1 associated protein 1
• GRIP1-associated protein 1
• GRIPAP1
• KIAA1167MGC126593
• MPMGp800B12492Q3

Background

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIPAP1
• Entrez:
  • 160622(Human)
  • 56149(Mouse)
  • 192254(Rat)
• Uniprot:
  • Q9JHZ4(Rat)